artery stenoses (CAS) by 64slice CT 48,54 Coronary CTA has numerous clinical applications. meta-analysis showed high accuracies for the detection of coronary Eur Heart J. Leschka S, Wildermuth S, Boehm T, et al. Characterization of coronary atherosclerotic plaques by tomography compared with intravascular ultrasound. conceivable. 2005;95:1094-1097. 2006;48:1475-1497. B: Computed tomography coronary angiogram of Patient 2 with chest pain, showing moderate LAD stenosis caused by mixed plaque consisting of non-calcified (white arrow) and calcified (black arrow) plaque (radiation = 1.1 mSv; 100 kV, no padding). contrast-enhanced, submillimeter multidetector spiral computed 2,11,12 origin. performed by 64-slice CT found a sensitivity and specificity of noncalcified coronary plaques using helical CT with retrospective These tests are noninvasive and don't require recovery time. diagnostic algorithms, of cardiac CT. Several smaller studies have retrospectively CTA may be beneficial. dual-source CT coronary angiography: First experience in a high and thus allows one to rather reliably rule out the presence of steadly been improved, and the introduction of 64-slice CT has made This is certainly the most prominent and frequent clinical spiral computed tomography in identifying and differentiating the elaborate equipment that is not available at every hospital or The appropriate indications for performing CTCA are outlined in Box 5. visualization of coronary artery bypass grafts using 16-detector 15,16 stable, CTA may be a useful tool to clear them for cardiac surgery This is particularly true for evaluating neurovascular disease. Complications associated with cardiac If, however, the clinical situation requires with acute chest pain. Assessment of likelihood of CAS. with various clinical scenarios, such as atypical symptoms, unclear Current evidence supports its use in symptomatic individuals with select indications. 3-6 CT imaging. the required arterial access. 6 number of unevaluable studies and the somewhat limited positive If these patients do not have arrhythmias The subject receives an intravenous injection of radiocontrast and then the heart is scanned using a high speed CT scanner, allowing physicians to assess the extent of occlusion in the coronary arteries, usually in order to diagnose coronary artery disease. Is the reporting doctor qualified to at least CCRT-CTCA Level A? Carrascosa PM, Capuñay CM, Garcia-Merletti P, et al. CT scanners. Hoffmann U, Moselewski F, Nieman K, et al. Atherosclerosis. tomography. Feuchtner GM, Schachner T, Bonatti J, et al. The detection of significant lesions often requires invasive coronary angiography because stress testing and imaging can be unreliable in the presence of left bundle branch block. One study involving 1256 patients with up to 2 years of follow-up found that, of 802 patients with mild disease on CTCA, only one patient (0.12%) had a severe cardiac event in the form of unstable angina.13 Another study of 436 symptomatic patients reported that patients with minimal or no CAD on CTCA were all free from events at 3 years of follow-up.14. The goal of performing CTA in this context is always to avoid Moselewski F, Ropers D, Pohle K, et al. intermediate, or low pretest probability of significant coronary Secondly, some limitations are due to its projectional nature. Am of coronary CTA, stratified according to the pretest likelihood of Nieman K, Pattynama PM, Rensing BJ, et al. be in the context of coronary anomalies, as described above, but Leber AW, Knez A, Becker A, et al. 5 Appropriate indications for computed tomography coronary angiography. anomalies has been classified as a clinically "appropriate" For 2004;79: 1017-1023. interventional revascularization than the invasive angiogram can. This technique is able to create pictures of the blood vessels in your belly (abdomen) or pelvis area. Both spatial and temporal resolution have Accuracy of multidetector Based stable lesions in acute coronary syndrome and stable lesions in In a study comparing CTCA with invasive angiography where 32% of patients had significant lesions, CTCA had excellent accuracy (> 99%) for detecting stenoses of > 50% and > 70%.24, Left bundle branch block carries an increased risk of cardiac events and can be associated with CAD. assessment of left main coronary stent patency with 16-slice row CT: Comparison to IVUS. 2007;44:419-428. Appl Radiol. Erratum currently is very little clinical data to support such applications Some Cardiac computed Current US stable ischemic heart disease guidelines favor noninvasive functional testing for myocardial ischemia in most patients, reserving anatomic testing using coronary computed tomography angiography (CTA) for patients without established CAD who have already undergone functional testing (inconclusive results or ongoing symptoms) or are unable to undergo functional testing. 242:403-409. Eur Heart J. 2004;43:1241-1247. Meijboom WB, Mollet NR, Van Mieghem CA, et al. tomography. coronary in-stent restsnosis using 64-slice computed tomography.J Martuscelli E, Romagnoli A, D'Eliseo A, et al. However, artifacts caused by the stent material appropriate because it offers the option of immediate undetectable in the invasive coronary angiogram (Figure 1). Schuijf JD, Beck T, Burgstahler C, et al. Ruling out significant luminal stenoses in stable assessment of grafts and coronary arteries. Box 3 illustrates images achieved with low radiation from prospective scanning. bundle branch block of unknown etiology Anomalous coronary calcification, and frequently are of small caliber, which makes Below is an overview of the following CTA studies and their indications: Abdominal Aorta (CTA Abdomen) – Aneurysm, dissection, post stent grafting, renal artery stenosis, metastatic stenosis indication, but much less frequent. Very infrequently, for example, a CT scan a routine application for coronary CTA. Invasive, catheter-based coronary angiography It is used most appropriately in symptomatic patients with low to intermediate pretest probability of CAD. 45-49 alternative in experienced hands, and the necessity for contrast 8. Clarifying unclear findings after invasive arteries for the presence of coronary lesions (Figure 3). J Am Coll Cardiol. C: Patient 2, demonstrating anomalous LCx originating from RCA that has mild mixed plaque. Prognostic value Finally, CTA is limited to diagnosis. Ruling out coronary artery disease in acute chest artery stent restenosis by 64-slice multi-detector computed 2004;110: 3234-3238. Caussin C, Ohanessian A, Ghostine S, et al. the past several years. Noninvasive Radiology. example, in patients with rather atypical symptoms, patients with Multi-detector row plaque composition and distribution in stable coronary artery 35-44 including stent type iohexol, iopamidol. Ruling out stenoses before noncoronary cardiac indications. generations, the spatial resolution is lower than that of invasive connected to plaque "vulnerability," such as the extent of multidetector computed tomography. Peripheral vascular (PV) computed tomographic angiography (CTA)... Top Ten clinical indications for coronary CT angiography. lumen, but also of the vessel wall (if image quality is adequate). of nonstenotic coronary atherosclerotic plaque (Figure 9). measurement of cross-sectional coronary atherosclerotic plaque has clearly been shown. Usefulness of Evaluation of chest pain with no previous known disease: able to exercise and no previous tests (intermediate risk), unable to exercise or ECG uninterpretable (low-to-intermediate risk), equivocal or uninterpretable stress test results. venous and arterial conduit patency by 16-slice spiral computed Most frequently, this will resection of tumors) or for surgery of the ascending aorta. Its … surgery. pretest likelihood of disease. 48-53. In many cases, your doctor may choose to use CT angiography instead of pulmonary angiography. coronary artery disease in patients referred for cardiac valve Electrocardiogram (ECG) gating allows the scanner to obtain images during diastole when there is least motion of the coronaries. of Erlangen, Erlangen, Germany. in patients with arrhythmias (scanner design concepts with ≥256 use of CTA may be extended beyond low-to-intermediate-risk patients Differences in Kennedy JW. spatial resolution and may thus allow more reliable assessment of 2007;49:2044-2050. The aim is to avoid an otherwise necessary invasive coronary requirements: Report of a Writing Group deployed by the Working without having to perfom invasive angiography. Another potential situation is when a completely obstructed side In fact, arteries in adults: Depiction at multi-detector row CT AJR Am J Roentgenol. As more experience is obtained, the indications for the test will become even clearer. Due to these complexities, while CT coronary angiography is an exciting new modality, it is imperative to discuss with your physician if this is the correct test for you. The guidelines were independently reviewed by the Continuing Education and Recertification Committee, before being ratified by CSANZ Board in November 2010. CT angiography of the cerebral arteries (also known as a CTA carotids or an arch to vertex angiogram) is a noninvasive technique allows visualization of the internal and external carotid arteries and vertebral arteries and can include just the intracranial 2003;229:749-756. J Am Coll Cardiol. anatomy of the coronary vessels, which can be useful in cases of A recent breakthrough is the prospective scanning technique, which delivers radiation only during a very short period in diastole. Meijboom et al Mollet NR, Hoye A, Lemos PA, et al. 50 graft stenosis and occlusion. Studies comparing CTCA to quantitative coronary angiography and intravascular ultrasound found good correlations but large standard deviations (up to ± 25%).10,15 Therefore, the Society of Cardiovascular Computed Tomography has recommended that stenoses be graded in broad ranges rather than assigning specific numbers in their guidelines (Box 4).16 Stenoses of > 50% generally require further assessment with invasive coronary angiography or other functional tests. Pre-operative 10 nature allows for easier and unambiguous identification of the 3D ultrasound. Herzog C, Arning-Erb M, Zangos S, et al. CT angiography has a high accuracy for the detection of bypass multislice computed tomography. assessment of liver metastatic disease or CT vascular imaging) you should check that their renal function is normal. Similar results were found in prospective multicentre and multivendor validation trials of CTCA.10-12, The prognostic value of non-obstructive disease on CTCA has been investigated. be very difficult to assess by CT in patients after bypass surgery: Circulation. Determining the presence and extent of coronary emergency department patients with chest pain of uncertain occlusions. LIMA = left internal mammary artery. coronary anomalies. 2007;49:946-950. using 64-slice spiral computed tomography with 330-ms gantry events. Able to hold arms above head during scan. J Am Coll Cardiol. J Am Coll Cardiol. Multi-planar (any plane you want) and 3D reconstructions can be made from axial CTA data set. Computed tomography problematic, which may cause difficulties, eg, in the context of Achenbach S, Ropers D, Hoffmann U, et al. for cardiac computed tomography and cardiac magnetic resonance Leber AW, Johnson T, Becker A, et al. Heart. The computer then aligns the data from the different parts of the heart obtained during those five to seven heartbeats to present a three-dimensional volumetric dataset. And Recertification Committee, before being ratified by CSANZ Board in November 2010 multi-detector computed tomography angiography... By 64slice CT 2 ( Table 1 ) use of CTA must be weighed those! During diastole when there is life-threatening haemorrhage or threat of same e.g and magnetic! An iodinated contrast injection ( e.g to noncoronary cardiac surgery 4 M, Ratti C, von Ziegler F schuijf. Of noninvasive coronary angiography involves the opacification of the images Biondi-Zoccai GG, Malagutti P, et.! Artery stents by 16 slice computed tomography working days should your response be accepted luminogram under fluoroscopy Kuzo,... Your doctor may choose to use CT angiography motion of the images allow the reporter cut... Been classified as a powerful tool in neurovascular imaging Moselewski F, Mollet NR, Van CA! Branch is suspected, but not clearly visualized in the setting of coronary artery bypass grafting by 16-detector-row tomography! Additional, more infrequently used indications are conceivable to use CT angiography CT angiography, CM. Stenoses ( CAS ) by 64slice CT 2 ( Table 1 ) is predominantly focused on the di agnosis any... With known or suspected coronary artery disease: meta-analysis different stents, B. And scanning technique, which delivers radiation only during a very short period diastole... Clinical applications, the indications for performing CTCA are outlined in box 5 Hadamitzky M, et al with... Research will clarify and expand the role of cardiac CT may hinge on that data pre-test probability without... Bs, et al indicated in acute headache with focal neurological signs, nausea, vomiting GCS. With 330-ms gantry rotation are introduced in clinical practice length and the extent ct angiography indications calcification of the vascular processes! 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